Izakhiwo ze-pharmacological kanye ne-toxicological ze-furazolidone zibuyekezwe kafushane. Phakathi kwezenzo ezibaluleke kakhulu ze-pharmacological ze-furazolidone ukuvinjelwa kwemisebenzi ye-mono- ne-diamine oxidase, okubonakala sengathi incike, okungenani kwezinye izinhlobo, ebukhoneni bezitshalo zamathumbu. Umuthi futhi ubonakala uphazamisa ukusetshenziswa kwe-thiamin, okungenzeka ukuthi iwusizo ekukhiqizeni i-anorexia kanye nokuncipha kwesisindo somzimba wezilwane ezilashwayo. I-Furazolidone yaziwa ngokudala isimo se-cardiomyopathy kuma-turkeys, engasetshenziswa njengemodeli ukutadisha ukuntula kwe-alpha 1-antitrypsin kumuntu. Umuthi unobuthi kakhulu ezilwaneni ezelusayo. Izimpawu ezinobuthi ezabonwa kwakungezokwethuka. Ukuhlolwa kuyaqhubeka kule labhorethri ukuzama ukuchaza indlela(izi)ndlela okwenziwa ngazo lobu buthi. Akuqinisekwa ukuthi ukusetshenziswa kwe-furazolidone ngethamo elinconyiwe lokwelapha kungaholela ezinsalela zezidakamizwa ezicutshini zezilwane ezilashwayo. Lolu wudaba olubalulekile empilweni yomphakathi njengoba umuthi ukhonjiswe ukuthi unomsebenzi we-carcinogenic. Kubalulekile ukuthi kuqanjwe indlela elula nethembekile yokuhlonza kanye nokulinganisa kwezinsalela ze-furazolidone. Kudingeka umsebenzi owengeziwe ukuze kucaciswe indlela yokwenza kanye nemiphumela ye-biochemical ebangelwa umuthi kukho kokubili umsingathi kanye nezinto ezithathelwanayo.
Isikhathi sokuthumela: Oct-08-2021