Endosulfan ndi mankhwala ophera tizilombo toyambitsa matenda a organochlorine omwe amatha kukhudzana ndi poyizoni m'mimba, kuchuluka kwa tizilombo toyambitsa matenda, komanso zotsatira zokhalitsa. Itha kugwiritsidwa ntchito pa thonje, mitengo yazipatso, masamba, fodya, mbatata ndi mbewu zina pofuna kuthana ndi nyongolotsi za thonje, nyongolotsi zofiira, zogudubuza masamba, kafadala za diamondi, ma chafers, nyongolotsi za pear heartworms, pichesi heartworms, armyworms, thrips ndi leafhoppers. Lili ndi zotsatira za mutagenic pa anthu, limawononga dongosolo lapakati la mitsempha, ndipo limayambitsa chotupa. Chifukwa cha kawopsedwe kake, bioaccumulation ndi endocrine zosokoneza, kugwiritsidwa ntchito kwake kwaletsedwa m'maiko opitilira 50.