nkhani

Makhalidwe a pharmacological ndi toxicological a furazolidone adawunikiridwa mwachidule. Zina mwa zinthu zofunika kwambiri za pharmacological za furazolidone ndizolepheretsa ntchito za mono- ndi diamine oxidase, zomwe zimawoneka kuti zimadalira, makamaka mwa mitundu ina, pakukhalapo kwa zomera za m'matumbo. Mankhwalawa akuwonekanso kuti amasokoneza kagwiritsidwe ntchito ka thiamin, yemwe mwina amathandizira pakupanga matenda a anorexia komanso kuchepa kwa thupi la nyama zolandilidwa. Furazolidone imadziwika kuti imayambitsa matenda a cardiomyopathy mu turkeys, zomwe zingagwiritsidwe ntchito ngati chitsanzo kuphunzira kuchepa kwa alpha-antitrypsin mwa munthu. Mankhwalawa ndi oopsa kwambiri kwa nyama zolusa. Zizindikiro zapoizoni zomwe zinawonedwa zinali zamanjenje. Kuyesera kukuchitika mu labotale iyi kuyesa kufotokoza njira (zi) zomwe kawopsedwewa amabweretsera. Sizikudziwika ngati kugwiritsa ntchito furazolidone pa mlingo woyenera wochizira kungabweretse zotsalira za mankhwala mu minofu ya nyama zochizira. Iyi ndi nkhani yofunika kwambiri paumoyo wa anthu chifukwa mankhwalawa awonetsedwa kuti ali ndi carcinogenic. Ndikofunikira kuti njira yosavuta komanso yodalirika yodziwira komanso kuyerekezera zotsalira za furazolidone zipangidwe. Ntchito yochulukirapo ikufunika kuti timvetsetse momwe zimagwirira ntchito komanso zotsatira zamankhwala am'thupi zomwe zimayambitsidwa ndi mankhwalawa m'zamoyo zonse zokhala ndi matenda.