M'zaka zaposachedwapa, khalidwe ndi chitetezo cha tiyi wakopa kwambiri ndi chidwi. Zotsalira za mankhwala ophera tizilombo zopitirira muyezo zimachitika nthawi ndi nthawi, ndipo tiyi wotumizidwa ku EU nthawi zambiri amadziwitsidwa za kupitirira muyezo.
Mankhwala amagwiritsidwa ntchito kupewa tizirombo ndi matenda panthawi yobzala tiyi. Pogwiritsa ntchito kwambiri mankhwala ophera tizilombo, zotsatira zoipa za zotsalira za mankhwala ophera tizilombo mopitirira muyeso, zosayenera kapena zogwiritsidwa ntchito molakwika pa thanzi la munthu, chilengedwe cha chilengedwe ndi malonda akunja zikuwonekera kwambiri.
Pakalipano, njira zodziwira zotsalira za mankhwala ophera tizilombo mu tiyi makamaka zimaphatikizapo gawo lamadzimadzi, gawo la gasi, ndi ultra-high performance liquid chromatography-tandem mass spectrometry.
Ngakhale njirazi zili ndi chidwi chodziwikiratu komanso zolondola, ndizovuta kuzifalitsa pamlingo wapansi pogwiritsira ntchito zida zazikulu za chromatographic, zomwe sizothandiza pakuwunika kwakukulu.
Njira yoletsa ma enzyme yomwe imagwiritsidwa ntchito powunika mwachangu zotsalira za mankhwala ophera tizilombo amagwiritsidwa ntchito makamaka pozindikira zotsalira za organophosphorus ndi carbamate mankhwala ophera tizilombo, omwe amasokonezedwa kwambiri ndi matrix ndipo amakhala ndi chiwopsezo chachikulu chabodza.
Khadi yozindikira golide ya Kwinbon itengera mfundo ya competitive inhibition immunochromatography.
Zotsalira za mankhwala mu zitsanzo zimachotsedwa ndikuphatikizidwa ndi antibody yeniyeni ya colloidal yolembedwa ndi golide kuti alepheretse kuphatikiza kwa antibody ndi antigen pamzere woyesera (T mzere) mu mzere woyesera, zomwe zimapangitsa kusintha kwa mtundu wa mayeso mzere.
Zotsalira za mankhwala ophera tizilombo m'zitsanzo zimatsimikiziridwa mwaluso poyerekezera kuya kwa mtundu wa mzere wodziwikiratu ndi mzere wowongolera (C mzere) poyang'ana maso kapena kutanthauzira zida.
Chowunikira chachitetezo chazakudya ndi chida chanzeru chotengera muyeso, kuwongolera ndi matekinoloje ophatikizidwa.
Amadziwika ndi ntchito yosavuta, kuzindikira kwakukulu, kuthamanga kwambiri komanso kukhazikika kwabwino, kufanana ndi mzere wodziwikiratu mwamsanga, kungathandize ogwiritsa ntchito m'munda mwamsanga komanso molondola zotsalira za mankhwala mu tiyi.
Nthawi yotumiza: Aug-03-2023