Lub pharmacological thiab toxicological zog ntawm furazolidone tau raug tshuaj xyuas luv luv. Ntawm qhov tseem ceeb tshaj plaws pharmacological kev ua ntawm furazolidone yog inhibition ntawm mono- thiab diamine oxidase kev ua ub no, uas zoo li nyob ntawm seb, yam tsawg kawg hauv qee hom, ntawm qhov muaj cov plab hnyuv. Cov tshuaj kuj zoo li cuam tshuam nrog kev siv thiamin, uas yog qhov tseem ceeb hauv kev tsim cov anorexia thiab poob ntawm lub cev hnyav ntawm cov tsiaj kho. Furazolidone paub tias yuav ua rau muaj mob cardiomyopathy hauv qaib cov txwv, uas tuaj yeem siv los ua tus qauv los kawm txog alpha 1-antitrypsin deficiency hauv txiv neej. Cov tshuaj yog tshuaj lom tshaj plaws rau ruminants. Cov cim tshuaj lom neeg pom tau ntawm cov hlab ntsha. Cov kev sim no tab tom ua tiav hauv chav kuaj no los sim piav qhia txog cov txheej txheem uas qhov kev toxicity no tshwm sim. Nws tsis paub meej tias kev siv furazolidone ntawm cov tshuaj kho tau pom zoo yuav ua rau cov tshuaj seem hauv cov ntaub so ntswg ntawm cov tsiaj kho. Qhov no yog ib qho teeb meem ntawm pej xeem kev noj qab haus huv tseem ceeb vim tias cov tshuaj tau pom tias muaj cov kab mob carcinogenic. Nws yog ib qho tseem ceeb uas txoj kev yooj yim thiab txhim khu kev qha ntawm kev txheeb xyuas thiab kwv yees ntawm furazolidone residues raug tsim. Kev ua haujlwm ntau ntxiv yog xav tau los piav qhia txog hom kev ua haujlwm thiab cov teebmeem biochemical tshwm sim los ntawm cov tshuaj hauv ob qho tib si tus tswv tsev thiab cov kab mob sib kis.
Post lub sij hawm: Oct-08-2021